This is a huge play for me:
Memphis +10 I have watched many Gonzaga games over the last few years, including this season. This is the weakest Gonzaga team in the last 4-5 seasons. Chet Holmgren really is a special player, but he has rarely been challenged by a C at his level all year. Duke and Alabama both beat Gonzaga because they could contain Holmgren reasonably well. Jalen Duren will do the same. Gonzaga also has 3 guys that get it done for them offensively, and except for St. Marys in their conference, they don't get challenged defensively all that much. Even with better Gonzaga teams of the past, their weak conference schedule does not prepare them for the physical nature and skill of the NCAA Tourney. So they never win the title. Memphis is a handful, and with Emoni Bates back, even more so. Would not be surprised to see them win this game, so a little on the ML.
Medium plays:
New Mexico St +6.5 Arkansas played Vermont a little too passively. If Vermont had a little more height and hit a few FTs 2nd half, they win. Also would not be surprised to see an outright upset here.
UNC +5.5 UNC's easy 1st round win was not a fluke. After getting beat by Duke at home, they have been the ACC's top squad. Their loss in the ACC final was a wakeup, but I think they'll give Baylor a tough game, and possibly upset them. Can both last year's finalists get beat on the same day in the 2nd round? Yes.
Tennessee -6 Michigan played a great 2nd half 1st round, but man, this team is full of flaws. The Vols just seem like a top 3 team right now and their team defense is really good right now.