Ervin Santana has show positively nothing to convince, especially not versus the Rangers, against whom he has a dreadful track record (6.46 career ERA).
Even if you narrow those games against Texas to those played at Angel Stadium, sure, he has four quality starts in five tries, but he also was hammered for eight runs on 10 hits, two of them home runs, in 5 2/3 innings as recently as Sept. 27, 2008 (when he was a heck of a lot healthier than he is today).
The Mariners, Orioles and White Sox all have handled him in his home starts in his past three turns there, and this is a loaded lineup.