I'm on Arizona for the Thursday night game.
Losing Bowman is hugeeeeee for the 49ers defense. Not only is he responsible for calling plays, he also makes sure all the players are in the right position, etc before the snap. Once he left the game vs Cowboys, the rush defense was comical. Ezekiel Elliott was running through holes so big...it was like a high school game. There's no way the 49ers can make the necessary adjustments by Thursday. There's absolutely no one on the defense that can replace Bowman. The roster is thin as shit due to horrible drafting and sitting on $50 Million cap space that they didn't use during the off season.
The 49ers have no home field advantage. During Sundays game I could hear the crowd chanting "Cowboys Cowboys Cowboys". Its NEVER loud when the opponent is on offense. I doubt Arizona will be effected by the crowd at all. Levi stadium is horrible and the niner fans have given up on the season. I'm not sure how many points the line is shaded towards the niners here due to home field advantage...but it shouldnt be more than 1 point.
I trust the Arizona coaching staff to do a better job getting the team prepared on a short week. Stanton has been with the team for 3 seasons now and he's familiar with the system. The Cards have a bunch of veterans who know the importance of this game...if they lose this their season is over. The Cards have issues, but for this week they will do enough to beat the niners.
I will also be on some David Johnson props...niners front 7 without Bowman is going to be pathetic. With Stanton starting, the Cards should lean on the run all night long.