There are times when I place a wager in-game. For example, tonight we have the Nats vs DBacks. And the DBacks get out to an early 1-0 lead. I may be able to get the Nats at -120 rather than pre-game at -210. I'm not planning on this play per se, just an example. With the quickness you need to put in these bets, I'm sure there are many stupid bets placed. I believe if you go into a game planning on placing live wagers, you need to have your strategy planned out before hand. It's also helpful to be actually watching the game so as to get a feel for things like body language, does the pitcher have good stuff, or are the batters hitting the ball hard, but right at people. etc.