My bet would be San Diego or the Colts.
I think New Orleans can cover, but not win. Colts have a small chance, but I could see them coming out flat after such an emotional game last week. San Diego is hot, playing well on both sides of the ball, and didn't need much to beat the Bengals, who flat out shit the bed.
I think this is the same trap that everyone falls into every year. There are (seemingly) more BIG road dogs in the playoffs. There shouldn't be near double-digit spreads in the 2nd round of the playoffs IMO. There shouldn't be such a disparity between the top and the bottom. Public will see Denver and all the records and easily lay 10 at home against the wild card team. Favorites to win the Super Bowl VERY RARELY do so, which means at least one of this upsets will hit this round or the next.