I don't think you have a lot of time after deplaning, to leave the aiport on a Sat Night, roll down the strip and get back to recheck in, go thru security etc.
zackzk- You're not going to have much time as Joey C said. Traffic is a bitch even that late. I would suggest a quick trip to Club Paradise. Good strip joint and some really beautiful women. It's very close to the airport so you can get there and back in plenty of time.
Spearmint Rhino is nice.
Ask a local (a chick dealer) what clubs are happening on the days you are there. Every day a certain club is the hot spot. IE, Ra is the place on this day, 54 another. The Beach is a pretty cool spot too.