There are so many factors to take into account here.
If you own a home, you can deduct your mortgage interest and property taxes on Schedule A when you itemize your deductions. However since I'm assuming you were already taking the standard deduction, the additional deductions might not be a large as you expect.
For instance, in my case for 2004 I could choose between the standard deduction of $9,700 since I'm married or I could itemize. After factoring in state and local income taxes, property taxes, home mortgage interest and charitable deductions my total itemized deductions were about $16,700. Therefore by itemizing I was able to reduce my AGI by seven grand.
Homeownership is not cheap. If something breaks, you don't call the landlord. You either call an expert or head over to Home Depot and fix it yourself. Also you have to remember all the other costs of upkeep (grass mowing, shoveling snow, raking leaves, etc).
Homeownership does have benefits, you're builiding equity with every mortgage payment you make. Also property values generally increase each year. Recently there has been a huge increase in property values and things may slow, but its unlikely most parts of the country will see any huge drops in property value. Regarding the downpayment, talk to your local bank or mortgage broker. There are ways around the standard 20% downpayment.
In general you are better off owning than renting, since buying a house in 1998, I now have approximately $100K in equity in this place with a mortgage payment that is not that much more than it would cost to rent a similar place.
one correction to Quantumleap's post, I believe that only the seller pays the RE agent's commission so if you are buying you don't have to worry about that. The 6% will come out of the seller's pocket, not the buyers.