B-12 defenses are suspect. Oregon can stuff the run and they have a couple of NFL caliber dbacks playing in this game that SHOULD have an effect as well. Jairus Byrd anb Patruick Chung will both be playing on Sundays.
Aside from that, in order to ask a question like you did, you have obviously never seen Johnson and Blount, Oregon's 2 RB play. I also think you've never seen Oregon QB Masoli run with the ball either (658 yards this year playing in only about 8 games.) Lately he's shown how well he can throw the ball too. But that's just been lately in his progress learning their offense, so nobody really knows what he's capable of except maybe those who have been following them.