Anytime the line is this high, I would take the dog or just not bother with the game.
The only time I've bet a line this high was the Florida-LA,Monroe game mentioned from 2001. I took the 56- points with Monroe. An early turnover from Florida let Monroe get 6 quick points. And Florida had a big game coming up the next week so even the mighty Steve Spurrier didn't waste time running the points up in the 4th quarter.
Keep in mind that for Oklahoma to cover a 52- point number, they really have to play nearly perfect football for 60 minutes. No turnovers, no back door touchdowns allowed in the second half, no special team miscues. And coming off a 77-0 win last week, I am sure the point spread is a little inflated.
Yes, Baylor is an awful team and is every year. Yes, there's a great chance they can lose 56-0 in this game or even worse. But taking Oklahoma hardly seems worth it.
Personally, I think the number is right on the money. 50-50 chance of a 49 point win and 50-50 chance of 56 point win. I don't see any value either way. With so many other games on the board, I think this is a good one to just not bother with.