8-7 ytd for top 5 picks. Here are the top consensus picks for week 5 for the top 50 leaders. Note there maybe some line differences.
| Team | # | Line |
| ARI | 28 | -2.5 |
| NE | 22 | -8.5 |
| CIN | 20 | -3 |
| NYG | 17 | -7 |
| ATL | 13 | -7 |
| CHI | 11 | 9 |
| DEN | 11 | -4.5 |
| GB | 11 | -9 |
| PHI | 11 | -4.5 |
| WAS | 11 | 7 |
| JAX | 10 | 3 |
| STL | 10 | 9 |
| CLE | 9 | 6.5 |
| OAK | 9 | 4.5 |
| HOU | 8 | -1 |
| SD | 8 | -3 |
| TEN | 8 | 2.5 |
| BUF | 7 | -2.5 |
| KC | 5 | -9 |
| PIT | 5 | 3 |
| SF | 4 | 7 |
| DAL | 3 | 8.5 |
| TB | 3 | -3 |
| BAL | 2 | -6.5 |
| NO | 2 | 4.5 |
| SEA | 2 | 3 |
