Gotta be hot from deep. They are really tough to finish against when penetrating because of all of their bigs.
When defending UK, I would pack everyone inside. Make UK shoot 3s and hope they're not hot. Although I'd try not to let Booker shoot any open 3s. He can drain them. But I do think you have to take your chances with the Harrison twins. I'd rather them beat me by making big shots than constantly allowing Towns and the other bigs to hit easy shots.