1) Read local media reports to find out injuries, whether new players are fitting in, etc.
2) Remember that past performance is no guarantee of future results. Disregard old angles.
3) Play the same style you normally play. If you are a dog bettor, fave bettor, totals bettor, moneyline bettor, prop bettor, etc., play the same style you will play the entire season.
And with all due respect to what was posted earlier in this thread, be careful about those short road favorites. If it looks too good to be true...