US President Barack Obama has said that Asia's security must not be based on intimidation where big nations bully small ones.
Mr Obama told students in Brisbane, Australia - where he is attending the G20 summit - that security in the region must depend on mutual alliances.
He said there was "no question" over US commitment to its Asia-Pacific allies.
The two-day G20 summit, which is getting under way, will focus on promoting growth.
World Leaders are expected to expand on plans agreed in February at the G20 finance ministers' meeting to boost global economic growth by 2% in five years.
Speaking just ahead of the meeting, the UN Secretary-General Ban Ki-Moon also urged those attending to meet the challenges posed by Ebola, climate change and the unresolved conflict in Ukraine.
Russian President Vladimir Putin is expected to face a hostile reception from some Western leaders concerned about Russia's increasing military assertiveness.