I prefer downtown most of the time. Better gambling. Better deals on good food. Everything close and within walking distance.
The only time I prefer the strip is on Sunday's during NFL season. I prefer to watch the games in a nice sportsbook when I bet them.
The past couple of years I've been staying at the Red Rock. Red Rock is just as nice as any Strip property. Has cheaper gaming. Good restaurants. And a nice sportsbook. Everything I want in 1 spot.