No, but if you must, Wil's road dog theory is good angle, as you get inflated numbers, and if a fav is gonna blow outright in surprise spots, many blow royal when doing it..to get all emissions out the tank.
Too dangerous with chalk, as they still are even or fav often, and many good teams get played off their @sses, while counting on their pens to close out one run games.
It's hard enough to just pick winners, let alone winners by 2 runs, in a game where the majority of stats are measured in three digit decimals.