tough call between Mad Men, The Wire, and Deadwood for me but gotta go Deadwood. Still pissed that HBO pulled it before it's conclusion.
Breaking bad was great for a couple of seasons but once the wife and her sister started whining and bitching every episode I had to eject. Those two were annoying as fuck and killed the show. BTW, anyone who says "its not even close" on something like this is a moron
Walking Dead is entertaining I guess but doesn't exist in the same hemisphere as MM, TW, and DW for me.
The Sopranos was a great show but probably lasted a few seasons too long
I just can't get into Game of Thrones...never made it past 4-5 episodes of Season One.
One not on this list that hasn't been mentioned is The Affair. Unique show that takes the same situation on each episode but splits it in half between two different view points. Top guy is McNulty from The Wire and the lead actress was the main woman on Luther which is the British show that stars The Wire's Stringer Bell. Those that love The Wire should dig The Affair....