I agree with Railbird - The Pony Express at SMU.
Eric Dickerson and Craig James. In 1981 alone Dickerson scored 19 touchdowns and gained 1400 plus yards. The next year Craig James became the first player since Rice's Billy Howton in 1951 to be named All-SWC at two positions, running back and punter.
The most storied duo though goes back to the 1940's when Army had a great team in the mid 40's led by the combo of Glenn Davis who played "Mr. Outside" to fullback Felix "Doc" Blanchard's "Mr. Inside". They combined to lead the greatest of all Army teams. The Cadets were undefeated national champions in 1944 and 1945 and undefeated with a tie in 1946, the year Davis won the Heisman. In those Davis-Blanchard years, Army went 27-0-1.
I know it's from back in the day but Mr. Inside and Mr. Outside were household names to all college football fans and for that matter the entire country during that era....
wil..