| Player | Team | Pos | Next Game (EST) | Injury | Status | Return Date |
| Dylan Carson | Air Force | RB | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Brandon Engel | Air Force | WR | Sep 7 7:00 PM | Lower Body | Doubtful | Sep 7th |
| Jared Roznos | Air Force | WR | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Alex Adams | Akron | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Ben Finley | Akron | QB | Sep 7 12:00 PM | Ribs | Questionable | Sep 7th |
| Myles Walker | Akron | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jalen Hale | Alabama | WR | Sep 7 7:00 PM | Knee | Out | Oct 5th |
| Kadyn Proctor | Alabama | OT | Sep 7 7:00 PM | Shoulder | Out | Sep 7th |
| Raleek Brown | Arizona State | RB | Sep 7 10:30 PM | Hamstring | Questionable | Sep 7th |
| Jayden Fortier | Arizona State | TE | Sep 7 10:30 PM | Undisclosed | Questionable | Sep 7th |
| Patrick Kutas | Arkansas | OG | Sep 7 12:00 PM | Back | Out | Sep 7th |
| Miguel Mitchell | Arkansas | S | Sep 7 12:00 PM | Undisclosed | Out | Sep 14th |
| Andrew Armstrong | Arkansas | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Zach Mundell | Army | QB | Sep 7 12:00 PM | Undisclosed | OFS | Mar 1st |
| Tyrell Robinson | Army | RB | Sep 7 12:00 PM | Knee | Out | Sep 26th |
| Brian Battie | Auburn | RB | Sep 7 3:30 PM | Head | OFS | Mar 1st |
| Alex McPherson | Auburn | K | Sep 7 3:30 PM | Illness | Questionable | Sep 7th |
| Bryson Washington | Baylor | RB | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Ethan Mikita | Boise State | RB | Sep 7 10:00 PM | Undisclosed | Doubtful | Sep 7th |
| Kaden Anderson | Boise State | TE | Sep 7 10:00 PM | Undisclosed | OFS | Mar 1st |
| Tyler Wegis | Boise State | DE | Sep 7 10:00 PM | Undisclosed | Out | Sep 7th |
| Jambres Dubar | Boise State | RB | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Zamondre Merriweather | Boise State | WR | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Austin Terry | Boise State | TE | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Grayson James | Boston College | QB | Sep 7 3:30 PM | Undisclosed | Doubtful | Sep 7th |
| Alex Broome | Boston College | RB | Sep 7 3:30 PM | Knee | OFS | Mar 1st |
| Jaylen Blackwell | Boston College | LB | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Cameron Martinez | Boston College | S | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Logan Taylor | Boston College | OT | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| PaSean Wimberly | Bowling Green | RB | Sep 7 12:00 PM | Undisclosed | OFS | Mar 1st |
| Nakai Amachree | Bowling Green | RB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| RJ Garcia II | Bowling Green | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Dom Grguric | Bowling Green | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Cynceir McNeal | Bowling Green | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Camden Orth | Bowling Green | QB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jaydn Ott | California | RB | Sep 7 3:30 PM | Undisclosed | Probable | Sep 7th |
| Kyion Grayes | California | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Justin Williams-Thomas | California | RB | Sep 7 3:30 PM | Knee | Questionable | Sep 7th |
| Jordan Davis | Central Florida | TE | Sep 7 6:30 PM | Achilles | OFS | Mar 1st |
| Tyson Davis | Central Michigan | WR | Sep 7 6:00 PM | Undisclosed | OFS | Mar 1st |
| Alec Palella | Central Michigan | TE | Sep 7 6:00 PM | Undisclosed | OFS | Mar 1st |
| Kadenn Rose | Central Michigan | RB | Sep 7 6:00 PM | Undisclosed | OFS | Mar 1st |
| Bert Emanuel | Central Michigan | QB | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Jacob Kaminski | Central Michigan | TE | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Marion Lukes | Central Michigan | RB | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Miles Shannon | Central Michigan | WR | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Mikah Coleman | Cincinnati | DE | Sep 7 12:00 PM | Lower Body | OFS | Mar 1st |
| Joey Beljan | Cincinnati | TE | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jarvis Green | Clemson | RB | Sep 7 8:00 PM | Lower Body | Questionable | Sep 7th |
| Peyton Streko | Clemson | RB | Sep 7 8:00 PM | Undisclosed | Questionable | Sep 7th |
| Max Balthazar | Coastal Carolina | RB | Sep 7 7:00 PM | Undisclosed | OFS | Mar 1st |
| Cordale Russell | Colorado | WR | Sep 7 7:30 PM | Undisclosed | Out | Nov 29th |
| Jaxxon Warren | Colorado State | TE | Sep 7 7:00 PM | Shoulder | OFS | Mar 1st |
| Jayden Moore | Duke | WR | Sep 6 9:00 PM | Knee | Doubtful | Sep 6th |
| Chase Sowell | East Carolina | WR | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Ja'Quavion Fraziars | Florida | WR | Sep 7 7:00 PM | Knee | Doubtful | Sep 7th |
| Gavin Hill | Florida | TE | Sep 7 7:00 PM | Upper Body | Doubtful | Sep 7th |
| Andy Jean | Florida | WR | Sep 7 7:00 PM | Wrist | Doubtful | Sep 7th |
| Keon Zipperer | Florida | TE | Sep 7 7:00 PM | Knee | Doubtful | Sep 7th |
| Graham Mertz | Florida | QB | Sep 7 7:00 PM | Concussion | Questionable | Sep 7th |
| BJ Alexander | Florida Atlantic | WR | Sep 7 12:00 PM | Undisclosed | OFS | Mar 1st |
| Destyn Hill | Florida State | WR | Sep 14 12:00 PM | Undisclosed | OFS | Mar 1st |
| Hykeem Williams | Florida State | WR | Sep 14 12:00 PM | Undisclosed | Questionable | Sep 14th |
| Josiah Freeman | Fresno State | WR | Sep 7 10:00 PM | Undisclosed | Doubtful | Sep 7th |
| Brandon Ramirez | Fresno State | RB | Sep 7 10:00 PM | Upper Body | Doubtful | Sep 7th |
| Tyler Carr | Fresno State | TE | Sep 7 10:00 PM | Lower Body | OFS | Mar 1st |
| Jacob Spomer | Fresno State | OT | Sep 7 10:00 PM | Knee | Out | Sep 7th |
| Tim Grear Jr. | Fresno State | WR | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Jake Tarwater | Fresno State | TE | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Roderick Robinson | Georgia | RB | Sep 7 2:00 PM | Toe | Out | Oct 5th |
| Dillon Bell | Georgia | WR | Sep 7 2:00 PM | Undisclosed | Probable | Sep 7th |
| Trevor Etienne | Georgia | RB | Sep 7 2:00 PM | Suspension | Questionable | Sep 7th |
| Ahmon Green | Georgia State | TE | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Jackson Long | Georgia Tech | TE | Sep 7 12:00 PM | Knee | OFS | Mar 1st |
| Brett Seither | Georgia Tech | TE | Sep 7 12:00 PM | Knee | OFS | Mar 1st |
| Trey Cooley | Georgia Tech | RB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Steven McBride | Hawaii | WR | Sep 14 7:00 PM | Not Injury Related | Doubtful | Sep 14th |
| Derek Boyd II | Hawaii | LB | Sep 14 7:00 PM | Knee | Out | Sep 14th |
| Sherman Smith | Houston | RB | Sep 7 7:45 PM | Foot | Doubtful | Sep 7th |
| Tony Mathis Jr. | Houston | RB | Sep 7 7:45 PM | Knee | OFS | Mar 1st |
| Caleb McMickle | Houston | QB | Sep 7 7:45 PM | Knee | OFS | Mar 1st |
| Steve Polk | Houston | RB | Sep 7 7:45 PM | Achilles | OFS | Mar 1st |
| Ajani Carter | Houston | CB | Sep 7 7:45 PM | Hip | Out | Sep 7th |
| Matt Byrnes | Houston | TE | Sep 7 7:45 PM | Groin | Questionable | Sep 7th |
| Cole Rusk | Illinois | TE | Sep 7 7:00 PM | Knee | OFS | Mar 1st |
| Andrew Depaepe | Indiana | DE | Sep 6 7:00 PM | Undisclosed | OFS | Mar 1st |
| Kaelon Black | Indiana | RB | Sep 6 7:00 PM | Hamstring | Questionable | Sep 6th |
| Brody Kosin | Indiana | TE | Sep 6 7:00 PM | Undisclosed | Questionable | Sep 6th |
| Donaven McCulley | Indiana | WR | Sep 6 7:00 PM | Neck | Questionable | Sep 6th |
| E.J. Williams Jr. | Indiana | WR | Sep 6 7:00 PM | Hamstring | Questionable | Sep 6th |
| Seth Anderson | Iowa | WR | Sep 7 3:30 PM | Undisclosed | Out | Sep 14th |
| Daniel Jackson | Iowa State | WR | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Brannon Spector | Jacksonville State | WR | Sep 7 3:30 PM | Elbow | OFS | Mar 1st |
| Dallan Wright | Jacksonville State | WR | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Ron Wiggins | Jacksonville State | RB | Sep 7 3:30 PM | Toe | Out | Oct 30th |
| Jordan Funk | James Madison | TE | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Taji Hudson | James Madison | WR | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| DeShawn Hanika | Kansas | TE | Sep 7 7:00 PM | Achilles | Out | Nov 30th |
| Keaton Kubecka | Kansas | WR | Sep 7 7:00 PM | Undisclosed | Out | Sep 13th |
| Jarred Sample | Kansas | WR | Sep 7 7:00 PM | Undisclosed | Questionable | Sep 7th |
| Gavin Garcia | Kent | RB | Sep 7 2:30 PM | Knee | OFS | Mar 1st |
| Nicholas Giacolone | Kent | LB | Sep 7 2:30 PM | Undisclosed | Out | Sep 7th |
| Dru DeShields | Kent | QB | Sep 7 2:30 PM | Undisclosed | Questionable | Sep 7th |
| Hardley Gilmore | Kentucky | WR | Sep 7 3:30 PM | Collarbone | Out | Oct 12th |
| Chip Trayanum | Kentucky | RB | Sep 7 3:30 PM | Hand | Out | Sep 14th |
| Josh Kattus | Kentucky | TE | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Brandon White | Kentucky | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Victor Jones | Liberty | WR | Sep 7 10:15 PM | Undisclosed | Doubtful | Sep 7th |
| Jack Turner | Louisiana Tech | QB | Sep 14 12:00 PM | Undisclosed | Questionable | Sep 14th |
| Jathan Caldwell | Louisiana-Lafayette | TE | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Charles Robertson | Louisiana-Lafayette | WR | Sep 7 7:00 PM | Academics | OFS | Mar 1st |
| KeDarius Wade | Louisiana-Lafayette | WR | Sep 7 7:00 PM | Suspension | Out | Sep 21st |
| Jordan Guerad | Louisville | DT | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Caullin Lacy | Louisville | WR | Sep 7 3:30 PM | Collarbone | Out | Oct 5th |
| Jimmy Calloway | Louisville | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Trey Holly | LSU | RB | Sep 7 7:30 PM | Undisclosed | Doubtful | Sep 7th |
| Kyle Parker | LSU | WR | Sep 7 7:30 PM | Elbow | Doubtful | Sep 7th |
| Chris Hilton | LSU | WR | Sep 7 7:30 PM | Ankle | Questionable | Sep 7th |
| Jelani Watkins | LSU | WR | Sep 7 7:30 PM | Foot | Questionable | Sep 7th |
| Isaiah Wright | Maryland | OT | Sep 7 3:30 PM | Lower Leg | OFS | Mar 1st |
| Quashon Fuller | Maryland | DE | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Jahmari Powell-Wonson | Maryland | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Sutton Smith | Memphis | RB | Sep 7 12:00 PM | Leg | Questionable | Sep 7th |
| Rueben Bain | Miami | DE | Sep 7 6:00 PM | Undisclosed | Out | Sep 7th |
| Isaiah Thomas | Miami | DB | Sep 7 6:00 PM | Undisclosed | Out | Oct 26th |
| Kenny Tracy | Miami (OH) | RB | Sep 14 12:00 PM | Undisclosed | OFS | Mar 1st |
| Rod Moore | Michigan | DB | Sep 7 12:00 PM | Knee | Out | Nov 2nd |
| Joe Taylor | Michigan | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jack Tuttle | Michigan | QB | Sep 7 12:00 PM | Elbow | Questionable | Sep 7th |
| Khalil Majeed | Michigan State | DB | Sep 7 3:30 PM | Lower Body | OFS | Mar 1st |
| Dillon Tatum | Michigan State | DB | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Alante Brown | Michigan State | WR | Sep 7 3:30 PM | Upper Body | Out | Nov 2nd |
| Wyatt Hook | Michigan State | TE | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Darius Green | Minnesota | S | Sep 7 12:00 PM | Undisclosed | Out | Sep 7th |
| Kaeden Johnson | Minnesota | RB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Darius Taylor | Minnesota | RB | Sep 7 12:00 PM | Hamstring | Questionable | Sep 7th |
| Pierce Walsh | Minnesota | TE | Sep 7 12:00 PM | Leg | Questionable | Sep 7th |
| Jeremy James | Mississippi | OG | Sep 7 4:15 PM | Hand | Out | Sep 28th |
| Logan Diggs | Mississippi | RB | Sep 7 4:15 PM | Knee | Questionable | Sep 7th |
| Jordan Watkins | Mississippi | WR | Sep 7 4:15 PM | Undisclosed | Questionable | Sep 7th |
| Seth Davis | Mississippi State | RB | Sep 7 10:30 PM | Knee | OFS | Mar 1st |
| Kelly Akharaiyi | Mississippi State | WR | Sep 7 10:30 PM | Undisclosed | Questionable | Sep 7th |
| Sam Horn | Missouri | QB | Sep 7 7:00 PM | Elbow | OFS | Mar 1st |
| Christopher Kreh | Missouri | RB | Sep 7 7:00 PM | Redshirt | OFS | Mar 1st |
| Darris Smith | Missouri | LB | Sep 7 7:00 PM | Knee | OFS | Mar 1st |
| Isaac Thompson | Missouri | S | Sep 7 7:00 PM | Undisclosed | OFS | Mar 1st |
| Brett Norfleet | Missouri | TE | Sep 7 7:00 PM | Undisclosed | Probable | Sep 7th |
| Theo Wease | Missouri | WR | Sep 7 7:00 PM | Undisclosed | Probable | Sep 7th |
| Regis Velez | Navy | WR | Sep 7 3:30 PM | Undisclosed | Doubtful | Sep 7th |
| Kroy Myers | Navy | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Demitrius Bell | Nebraska | WR | Sep 7 7:30 PM | Knee | OFS | Mar 1st |
| Teddy Prochazka | Nebraska | OT | Sep 7 7:30 PM | Knee | OFS | Mar 1st |
| Javin Wright | Nebraska | LB | Sep 7 7:30 PM | Undisclosed | Out | Nov 2nd |
| Chubba Purdy | Nevada | QB | Sep 7 7:00 PM | Shoulder | Probable | Sep 7th |
| Davis Mallinger | Nevada | DB | Sep 7 7:00 PM | Not Injury Related | Suspension | Sep 7th |
| Jaylen Morgan | New Mexico | RB | Sep 14 7:30 PM | Undisclosed | Questionable | Sep 14th |
| Max Johnson | North Carolina | QB | Sep 7 3:30 PM | Knee | OFS | Mar 1st |
| Caleb Hood | North Carolina | RB | Sep 7 3:30 PM | Lower Body | Questionable | Sep 7th |
| Isheem Young | North Texas | S | Sep 7 7:30 PM | Undisclosed | OFS | Mar 1st |
| Landon Sides | North Texas | WR | Sep 7 7:30 PM | Undisclosed | Questionable | Sep 7th |
| Raishein Thomas | Northern Illinois | DE | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Devon Akers | Northern Illinois | TE | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Kenji Lewis | Northern Illinois | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Jake Seibert | Northern Illinois | K | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Richie Hagarty | Northwestern | LB | Sep 6 9:00 PM | Undisclosed | Out | Sep 6th |
| Tate Crane | Northwestern | WR | Sep 6 9:00 PM | Undisclosed | Questionable | Sep 6th |
| Donnie Gray | Northwestern | WR | Sep 6 9:00 PM | Undisclosed | Questionable | Sep 6th |
| Carson Grove | Northwestern | WR | Sep 6 9:00 PM | Undisclosed | Questionable | Sep 6th |
| Charles Jagusah | Notre Dame | OT | Sep 7 3:30 PM | Upper Body | OFS | Mar 1st |
| Gi'Bran Payne | Notre Dame | RB | Sep 7 3:30 PM | Knee | OFS | Mar 1st |
| Jordan Faison | Notre Dame | WR | Sep 7 3:30 PM | Ankle | Out | Sep 14th |
| Eamonn Dennis | Ohio | WR | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| Max Rodarte | Ohio | WR | Sep 7 6:00 PM | Undisclosed | Questionable | Sep 7th |
| TC Caffey | Ohio State | RB | Sep 7 7:30 PM | Knee | OFS | Mar 1st |
| Jayden Bonsu | Ohio State | S | Sep 7 7:30 PM | Undisclosed | Out | Sep 7th |
| Donovan Jackson | Ohio State | OG | Sep 7 7:30 PM | Undisclosed | Out | Sep 7th |
| Cody Simon | Ohio State | LB | Sep 7 7:30 PM | Undisclosed | Out | Sep 7th |
| Reis Stocksdale | Ohio State | WR | Sep 7 7:30 PM | Undisclosed | Questionable | Sep 7th |
| Jayden Gibson | Oklahoma | WR | Sep 7 7:45 PM | Knee | OFS | Mar 1st |
| Jalil Farooq | Oklahoma | WR | Sep 7 7:45 PM | Foot | Out | Oct 12th |
| Nic Anderson | Oklahoma | WR | Sep 7 7:45 PM | Undisclosed | Questionable | Sep 7th |
| AJ Green | Oklahoma State | RB | Sep 7 12:00 PM | Leg | Out | Nov 2nd |
| Justin Wright | Oklahoma State | LB | Sep 7 12:00 PM | Undisclosed | Out | Oct 5th |
| Da'Wain Lofton | Oklahoma State | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jalen Pope | Oklahoma State | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jahlil Florence | Oregon | CB | Sep 7 10:00 PM | Undisclosed | Out | Sep 7th |
| Andrew Boyle | Oregon | K | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Travis Brashear | Oregon | TE | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Gary Bryant Jr. | Oregon | WR | Sep 7 10:00 PM | Undisclosed | Questionable | Sep 7th |
| Jamai East | Oregon State | WR | Sep 7 10:30 PM | Undisclosed | OFS | Mar 1st |
| Makiya Tongue | Oregon State | LB | Sep 7 10:30 PM | Lower Leg | Out | Sep 7th |
| Darrius Clemons | Oregon State | WR | Sep 7 10:30 PM | Undisclosed | Questionable | Sep 7th |
| Jailen Holmes | Oregon State | WR | Sep 7 10:30 PM | Undisclosed | Questionable | Sep 7th |
| Jimmy Valsin | Oregon State | WR | Sep 7 10:30 PM | Leg | Questionable | Sep 7th |
| Peter Gonzalez | Penn State | WR | Sep 7 12:00 PM | Undisclosed | Doubtful | Sep 7th |
| Zuriah Fisher | Penn State | DE | Sep 7 12:00 PM | Undisclosed | Out | Sep 7th |
| Keon Wylie | Penn State | LB | Sep 7 12:00 PM | Undisclosed | Out | Sep 7th |
| Jerry Cross | Penn State | TE | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Khalil Dinkins | Penn State | TE | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Jaxon Smolik | Penn State | QB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Rodney Hammond | Pittsburgh | RB | Sep 7 12:00 PM | Not Injury Related | OFS | Mar 1st |
| Nate Temple | Pittsburgh | DE | Sep 7 12:00 PM | Lower Leg | OFS | Mar 1st |
| Nyland Green | Purdue | DB | Sep 14 3:30 PM | Foot | Out | Sep 14th |
| CJ Smith | Purdue | WR | Sep 14 3:30 PM | Hamstring | Questionable | Sep 14th |
| Landon Ransom-Goelz | Rice | WR | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Mohamed Toure | Rutgers | DE | Sep 7 12:00 PM | Knee | OFS | Mar 1st |
| Wesley Bailey | Rutgers | DE | Sep 7 12:00 PM | Undisclosed | Out | Sep 7th |
| Flip Dixon | Rutgers | S | Sep 7 12:00 PM | Undisclosed | Out | Sep 7th |
| Tyreem Powell | Rutgers | LB | Sep 7 12:00 PM | Achilles | Out | Sep 7th |
| Edd Guerrier | Rutgers | RB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Dino Kaliakmanis | Rutgers | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| AJ Surace | Rutgers | QB | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Phillippe Wesley | San Diego State | WR | Sep 7 10:30 PM | Undisclosed | Doubtful | Sep 7th |
| Cincere Rhaney | San Diego State | RB | Sep 7 10:30 PM | Knee | OFS | Mar 1st |
| Kenan Christon | San Diego State | RB | Sep 7 10:30 PM | Ankle | Out | Oct 5th |
| Malikhi Miller | San Jose State | WR | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Camar Wheaton | SMU | RB | Sep 6 7:00 PM | Knee | OFS | Mar 1st |
| Braeden Flowers | SMU | DE | Sep 6 7:00 PM | Knee | Out | Sep 6th |
| Mike Yoan Sandjo-Njiki | SMU | DT | Sep 6 7:00 PM | Undisclosed | Out | Sep 6th |
| Jaylan Knighton | SMU | RB | Sep 6 7:00 PM | Undisclosed | Probable | Sep 6th |
| CJ Adams | South Carolina | WR | Sep 7 3:30 PM | Finger | Doubtful | Sep 7th |
| Bradley Dunn | South Carolina | RB | Sep 7 3:30 PM | Undisclosed | Doubtful | Sep 7th |
| Reid Mikeska | South Carolina | TE | Sep 7 3:30 PM | Undisclosed | Doubtful | Sep 7th |
| K'wan Powell | South Florida | RB | Sep 7 7:00 PM | Knee | Out | Oct 11th |
| Dannis Jackson | Southern Miss | WR | Sep 7 7:00 PM | Undisclosed | Out | Sep 14th |
| Marlowe Wax | Syracuse | LB | Sep 7 12:00 PM | Undisclosed | Out | Oct 24th |
| David Wohlabaugh Jr. | Syracuse | OT | Sep 7 12:00 PM | Leg | Out | Sep 7th |
| Justus Ross-Simmons | Syracuse | WR | Sep 7 12:00 PM | Hamstring | Questionable | Sep 7th |
| Major Everhart | TCU | WR | Sep 7 8:00 PM | Undisclosed | Out | Sep 21st |
| Hauss Hejny | TCU | QB | Sep 7 8:00 PM | Undisclosed | Out | Sep 21st |
| JoJo Earle | TCU | WR | Sep 7 8:00 PM | Undisclosed | Probable | Sep 7th |
| Dylan Wright | TCU | WR | Sep 7 8:00 PM | Undisclosed | Probable | Sep 7th |
| Ian Stewart | Temple | WR | Sep 7 3:30 PM | Quadriceps | OFS | Mar 1st |
| Diwun Black | Temple | LB | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Zae Baines | Temple | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Peter Clarke | Temple | TE | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Emmanuel Okoye | Tennessee | DT | Sep 7 7:30 PM | Undisclosed | OFS | Mar 1st |
| Jourdan Thomas | Tennessee | DB | Sep 7 7:30 PM | Knee | OFS | Mar 1st |
| Mike Matthews | Tennessee | WR | Sep 7 7:30 PM | Undisclosed | Questionable | Sep 7th |
| Braylon Staley | Tennessee | WR | Sep 7 7:30 PM | Undisclosed | Questionable | Sep 7th |
| CJ Baxter | Texas | RB | Sep 7 12:00 PM | Knee | OFS | Mar 1st |
| Christian Clark | Texas | RB | Sep 7 12:00 PM | Achilles | OFS | Mar 1st |
| Jabre Barber | Texas A&M | WR | Sep 7 12:45 PM | Foot | Doubtful | Sep 7th |
| Garrett Miller | Texas A&M | TE | Sep 7 12:45 PM | Ankle | Doubtful | Sep 7th |
| Mark Nabou | Texas A&M | OG | Sep 7 12:45 PM | Lower Leg | OFS | Mar 1st |
| Rueben Owens | Texas A&M | RB | Sep 7 12:45 PM | Lower Body | OFS | Mar 1st |
| Enai White | Texas A&M | DE | Sep 7 12:45 PM | Undisclosed | Out | Sep 7th |
| Joseph Adedire | Texas Tech | LB | Sep 7 10:00 PM | Knee | OFS | Mar 1st |
| Dylan Spencer | Texas Tech | OG | Sep 7 10:00 PM | Knee | OFS | Mar 1st |
| Tahj Brooks | Texas Tech | RB | Sep 7 10:00 PM | Arm | Questionable | Sep 7th |
| Javon Brown | Toledo | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Terrell Crosby Jr. | Toledo | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Michael Denning | Toledo | K | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Mike Drennen | Toledo | RB | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Lucas Laroche | Toledo | RB | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Kalieb Osborne | Toledo | QB | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Kristian Pechac | Toledo | RB | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Liam Quigley | Toledo | K | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Chris Lewis | Troy | WR | Sep 7 12:00 PM | Leg | OFS | Mar 1st |
| Shazz Preston | Tulane | WR | Sep 7 12:00 PM | Undisclosed | Questionable | Sep 7th |
| Hudson Habermehl | UCLA | TE | Sep 14 7:30 PM | Knee | OFS | Mar 1st |
| Troy Leigber | UCLA | RB | Sep 14 7:30 PM | Knee | OFS | Mar 1st |
| Gary Smith III | UCLA | DT | Sep 14 7:30 PM | Leg | Out | Sep 14th |
| Deshun Murrell | UCLA | RB | Sep 14 7:30 PM | Knee | Questionable | Sep 14th |
| Sam Summa | UCLA | TE | Sep 14 7:30 PM | Undisclosed | Questionable | Sep 14th |
| Malik Dixon-Williams | UConn | S | Sep 7 12:00 PM | Hand | Out | Sep 14th |
| Pryce Yates | UConn | DE | Sep 7 12:00 PM | Concussion | Out | Sep 7th |
| Nick Evers | UConn | QB | Sep 7 12:00 PM | Head | Questionable | Sep 7th |
| Jalar Holley | UNC Charlotte | DT | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Duane Thomas Jr. | UNC Charlotte | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Carson Tabaracci | USC | TE | Sep 7 11:00 PM | Neck | Questionable | Sep 7th |
| Kenan Johnson | Utah | CB | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Spencer Petras | Utah State | QB | Sep 7 11:00 PM | Undisclosed | Questionable | Sep 7th |
| De'Corian Clark | UTSA | WR | Sep 7 4:00 PM | Knee | Doubtful | Sep 7th |
| Nnanna Anyanwu | UTSA | LB | Sep 7 4:00 PM | Undisclosed | Out | Sep 7th |
| Makai Hart | UTSA | OT | Sep 7 4:00 PM | Undisclosed | Out | Sep 7th |
| Jaren Randle | UTSA | WR | Sep 7 4:00 PM | Leg | Out | Nov 2nd |
| Mark Davis | Vanderbilt | CB | Sep 7 7:30 PM | Achilles | OFS | Mar 1st |
| Brycen Coleman | Vanderbilt | TE | Sep 7 7:30 PM | Collarbone | Out | Oct 5th |
| Dariyan Wiley | Vanderbilt | WR | Sep 7 7:30 PM | Hamstring | Questionable | Sep 7th |
| JR Wilson | Virginia | WR | Sep 7 7:00 PM | Leg | Out | Sep 14th |
| Nick Gallo | Virginia Tech | TE | Sep 7 4:30 PM | Knee | Doubtful | Sep 7th |
| Jalen Stroman | Virginia Tech | S | Sep 7 4:30 PM | Undisclosed | Out | Oct 5th |
| Kyron Drones | Virginia Tech | QB | Sep 7 4:30 PM | Undisclosed | Probable | Sep 7th |
| Jeremiah Coney | Virginia Tech | RB | Sep 7 4:30 PM | Undisclosed | Questionable | Sep 7th |
| Tucker Holloway | Virginia Tech | WR | Sep 7 4:30 PM | Knee | Questionable | Sep 7th |
| Bhayshul Tuten | Virginia Tech | RB | Sep 7 4:30 PM | Undisclosed | Questionable | Sep 7th |
| David Egbe | Wake Forest | RB | Sep 7 7:00 PM | Undisclosed | Doubtful | Sep 7th |
| Michael Frogge | Wake Forest | TE | Sep 7 7:00 PM | Undisclosed | Questionable | Sep 7th |
| Charlie Crowell | Washington | TE | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Armon Parker | Washington | DT | Sep 7 3:30 PM | Undisclosed | OFS | Mar 1st |
| Russell Davis II | Washington | DT | Sep 7 3:30 PM | Undisclosed | Out | Sep 7th |
| Kevin Green Jr. | Washington | WR | Sep 7 3:30 PM | Leg | Out | Oct 26th |
| Ryan Otton | Washington | TE | Sep 7 3:30 PM | Undisclosed | Out | Sep 27th |
| Carlos Hernandez | Washington State | WR | Sep 7 10:00 PM | Foot | Out | Oct 12th |
| Rex Robich | Western Kentucky | C | Sep 7 7:00 PM | Undisclosed | Out | Sep 7th |
| Kenneth Womack | Western Michigan | WR | Sep 7 7:30 PM | Hand | Out | Oct 5th |
| James Thompson | Wisconsin | DE | Sep 7 3:30 PM | Upper Body | Out | Nov 29th |
| Rob Booker II | Wisconsin | TE | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Quincy Burroughs | Wisconsin | WR | Sep 7 3:30 PM | Undisclosed | Questionable | Sep 7th |
| Harrison Waylee | Wyoming | RB | Sep 7 3:30 PM | Knee | Out | Oct 12th |
| Dawaiian McNeely | Wyoming | RB | Sep 7 3:30 PM | Knee | Probable | Sep 7th |
| John Michael Gyllenborg | Wyoming | TE | Sep 7 3:30 PM | Lower Leg | Questionable | Sep 7th |
Added Play
Colorado whipped Nebraska in Boulder last year 36-14 as a 2.5 Point Favorite
Nebraska ...likely circled this game for some revenge
Why is Nebraska -7 at home ....after losing by 22 at Boulder ???
Feel ... payback coming
Play ..... Nebraska - 6 - 132
Plays
Texas / Michigan U 23 -144 1st Half
Texas - 3 - 140 / now -7 ( Your Call )
Iowa St / Iowa Under 19 - 161 1st Half
Auburn - 12 -140
Okla - 28 -140
Nebraska - 6 - 132
Colorado whipped Nebraska in Boulder last year 36-14 as a 2.5 Point Favorite
Nebraska ...likely circled this game for some revenge
Why is Nebraska -7 at home ....after losing by 22 at Boulder ???
Feel ... payback coming
Play ..... Nebraska - 6 - 132
Plays
Texas / Michigan U 23 -144 1st Half
Texas - 3 - 140 / now -7 ( Your Call )
Iowa St / Iowa Under 19 - 161 1st Half
Auburn - 12 -140
Okla - 28 -140
Nebraska - 6 - 132
