these are lines being offered by my book right now, hence fantasy game. Basically, whatever the team scores against their real opponent is used for their points in this fantasy matchup
If I'm reading this correctly, I'd be all over USC -4.5. Oklahoma will be playing a solid defense, while USC will score in the 40's, like they always do.
USC rolls up on some cupcake Ds in the Pac 10--they haven't faced anyone as physical as Michigan. I wouldn't count on them hanging 40 moreorless more than 24 on Michigan !!