Not on USC, but no way could I bet Wash and feel confident about it. This alone is scary.
<table class="data" cellpadding="2" cellspacing="1"><tbody><tr><td class="datahl2">Def</td><td class="datahl2">Avg</td><td class="datahl2">Yards</td><td class="datahl2">Pass</td><td class="datahl2">Rush</td><td class="datahl2">Y/R</td><td class="datahl2">Y/A</td></tr><tr><td class="datahl2">USC
WASH</td><td class="datacell">9.0
27.0</td><td class="datacell">193.0
366.5</td><td class="datacell">144.5
260.5</td><td class="datacell">48.5
106.0</td><td class="datacell">1.6
4.1
</td><td class="datacell">5.3
8.8
</td></tr></tbody></table>
then I keep seeing this from last year
<table class="data" cellpadding="2" cellspacing="1"><tbody><tr><td class="datahl2b" width="10%">Date</td><td class="datahl2b">Away/Home</td><td class="datahl2b">Line</td><td class="datahl2b">O/U</td><td class="datahl2b" width="8%">Tot</td><td class="datahl2b" width="8%">Rus</td><td class="datahl2b" width="8%">Pas</td></tr><tr><td class="datahl2">11/01/08</td><td class="datacell">
WASH 0 - USC 56</td><td class="datacell">USC -45.5</td><td class="datacell">P 56</td><td class="datacell" align="right">
-301</td><td class="datacell" align="right">
-226</td><td class="datacell" align="right">
-75</td></tr></tbody></table>
Line was -45 1/2 last year. I think they already adjusted from that as the line is what around -21.
Not saying USC covers, just saying why I wouldn't feel comfortable with the 21.