Dr. Harvey Risch has no skin in the game. No ties to any big pharma and is not in bed with Fauci. Yale and very well esteemed.
https://academic.oup.com/aje/article-pdf/doi/10.1093/aje/kwaa093/33381404/kwaa093.pdf
https://academic.oup.com/aje/article-pdf/doi/10.1093/aje/kwaa093/33381404/kwaa093.pdf
what does this have to do with data?
the only way to disprove the findings is to find error in the data or the statistical methods.
this is how science works. thinking one way or another about trump doesn't change the numbers.
fwiw, the new england journal of medicine is a peer-reviewed publication, and is one of the hardest to get published in. even your own doctors cannot disagree with that.
The new england journan of medicine is peer-reviewed. Thank you for that. Did you read up on the retracted Lancet study posted in the new england journal of medicine that caused the emergency order to be halted and caused many governors to ban HCQ? Let me grab that one for you.
https://www.theguardian.com/world/2...s-paper-that-halted-hydroxychloroquine-trials
This fake study caused just about every other ongoing study to halt and never be complete including two the NIH were doing. It is truly incredible once you did into it.
This fake study caused just about every other ongoing study to halt and never be complete including two the NIH were doing. It is truly incredible once you did into it.
This study with the addition of another study at Oxford (get to that one later), the FDA revoked Trump's emergency HCQ order. This study gets retracted yet the FDA says nothing, does nothing, and their order stands. Fauci didn't even acknowledge the retraction. This is what Fauci said after the Lancetgate:
"The scientific data is really quite evident now about the lack of efficacy,"
Whoops
"The scientific data is really quite evident now about the lack of efficacy,"
Whoops
HCQ + cocktail is definitely a good solution to the Chinese virus, not perfect, but when used wisely, is very effective.
It shows you how far the globalist/socialist/Democtat machine will go to take power in this country, they have ordered the media/press/Hollywood/social media giant to disparage the product, they have smeared all communications with misinformation and disinformation about HCQ = cocktail.
The people cannot have hope against this virus... the people must remain desperate: at least until November 4th.
(additionally, long story short, the CDC/NIH/FDA are not reliable at all these days)
It shows you how far the globalist/socialist/Democtat machine will go to take power in this country, they have ordered the media/press/Hollywood/social media giant to disparage the product, they have smeared all communications with misinformation and disinformation about HCQ = cocktail.
The people cannot have hope against this virus... the people must remain desperate: at least until November 4th.
(additionally, long story short, the CDC/NIH/FDA are not reliable at all these days)
[h=1]Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford Health System Study Shows [/h] July 02, 2020
DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System.
In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s six hospitals, the study found 13% of those treated with hydroxychloroquine alone died compared to 26.4% not treated with hydroxychloroquine. None of the patients had documented serious heart abnormalities; however, patients were monitored for a heart condition routinely pointed to as a reason to avoid the drug as a treatment for COVID-19.
The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).
Patients treated with hydroxychloroquine at Henry Ford met specific protocol criteria as outlined by the hospital system’s Division of Infectious Diseases. The vast majority received the drug soon after admission; 82% within 24 hours and 91% within 48 hours of admission. All patients in the study were 18 or over with a median age of 64 years; 51% were men and 56% African American
DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System.
In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s six hospitals, the study found 13% of those treated with hydroxychloroquine alone died compared to 26.4% not treated with hydroxychloroquine. None of the patients had documented serious heart abnormalities; however, patients were monitored for a heart condition routinely pointed to as a reason to avoid the drug as a treatment for COVID-19.
The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).
Patients treated with hydroxychloroquine at Henry Ford met specific protocol criteria as outlined by the hospital system’s Division of Infectious Diseases. The vast majority received the drug soon after admission; 82% within 24 hours and 91% within 48 hours of admission. All patients in the study were 18 or over with a median age of 64 years; 51% were men and 56% African American
http://www.francesoir.fr/societe-sante/covid-19-hydroxychloroquine-works-irrefutable-proof
Here's the article that explains those charts. Fake Lancet study comes out, Fauci and WHO issue their bans on HCQ and Azithro, France and Switzerland stop using except for trials. The Lancet study gets retracted, the use of HCQ and Azithro resume. Pretty crazy stuff.
Here's the article that explains those charts. Fake Lancet study comes out, Fauci and WHO issue their bans on HCQ and Azithro, France and Switzerland stop using except for trials. The Lancet study gets retracted, the use of HCQ and Azithro resume. Pretty crazy stuff.
[h=1]The Key to Defeating COVID-19 Already Exists. We Need to Start Using It | Opinion[/h] Harvey A. Risch, MD, PhD , Professor of Epidemiology, Yale School of Public Health
<time datetime="2020-07-23T07:00:02-04:00" data-timestamp="1595502002"> On 7/23/20 at 7:00 AM EDT
</time>As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.
I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.
On May 27, I published an article in the American Journal of Epidemiology (AJE) entitled, "Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis." That article, published in the world's leading epidemiology journal, analyzed five studies, demonstrating clear-cut and significant benefits to treated patients, plus other very large studies that showed the medication safety.
Physicians who have been using these medications in the face of widespread skepticism have been truly heroic. They have done what the science shows is best for their patients, often at great personal risk. I myself know of two doctors who have saved the lives of hundreds of patients with these medications, but are now fighting state medical boards to save their licenses and reputations. The cases against them are completely without scientific merit.
Since publication of my May 27 article, seven more studies have demonstrated similar benefit. In a lengthy follow-up letter, also published by AJE, I discuss these seven studies and renew my call for the immediate early use of hydroxychloroquine in high-risk patients. These seven studies include: an additional 400 high-risk patients treated by Dr. Vladimir Zelenko, with zero deaths; four studies totaling almost 500 high-risk patients treated in nursing homes and clinics across the U.S., with no deaths; a controlled trial of more than 700 high-risk patients in Brazil, with significantly reduced risk of hospitalization and two deaths among 334 patients treated with hydroxychloroquine; and another study of 398 matched patients in France, also with significantly reduced hospitalization risk. Since my letter was published, even more doctors have reported to me their completely successful use.
My original article in the AJE is available free online, and I encourage readers—especially physicians, nurses, physician assistants and associates, and respiratory therapists—to search the title and read it. My follow-up letter is linked there to the original paper.
Beyond these studies of individual patients, we have seen what happens in large populations when these drugs are used. These have been "natural experiments." In the northern Brazil state of Pará, COVID-19 deaths were increasing exponentially. On April 6, the public hospital network purchased 75,000 doses of azithromycin and 90,000 doses of hydroxychloroquine. Over the next few weeks, authorities began distributing these medications to infected individuals. Even though new cases continued to occur, on May 22 the death rate started to plummet and is now about one-eighth what it was at the peak.
<figure class="imageBox" style=""> <source type="image/webp" media="(min-width: 992px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/jpeg" media="(min-width: 992px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/webp" media="(min-width: 768px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=900&f=7ac996341f797b5565a3461434971a96 1x"><source type="image/jpeg" media="(min-width: 768px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=900&f=7ac996341f797b5565a3461434971a96 1x"><source type="image/webp" media="(min-width: 481px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/jpeg" media="(min-width: 481px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/webp" media="(min-width: 0px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=450&f=b4592c433b66d9a7442394696cfe6def 1x"><source type="image/jpeg" media="(min-width: 0px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=450&f=b4592c433b66d9a7442394696cfe6def 1x"><source type="image/webp" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1"> <figcaption class="caption"> </figcaption>
</figure>A reverse natural experiment happened in Switzerland. On May 27, the Swiss national government banned outpatient use of hydroxychloroquine for COVID-19. Around June 10, COVID-19 deaths increased four-fold and remained elevated. On June 11, the Swiss government revoked the ban, and on June 23 the death rate reverted to what it had been beforehand. People who die from COVID-19 live about three to five weeks from the start of symptoms, which makes the evidence of a causal relation in these experiments strong. Both episodes suggest that a combination of hydroxychloroquine and its companion medications reduces mortality and should be immediately adopted as the new standard of care in high-risk patients.
Why has hydroxychloroquine been disregarded?
First, as all know, the medication has become highly politicized. For many, it is viewed as a marker of political identity, on both sides of the political spectrum. Nobody needs me to remind them that this is not how medicine should proceed. We must judge this medication strictly on the science. When doctors graduate from medical school, they formally promise to make the health and life of the patient their first consideration, without biases of race, religion, nationality, social standing—or political affiliation. Lives must come first.
Second, the drug has not been used properly in many studies. Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. Even so, it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.
In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.
In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.
Third, concerns have been raised by the FDA and others about risks of cardiac arrhythmia, especially when hydroxychloroquine is given in combination with azithromycin. The FDA based its comments on data in its FDA Adverse Event Reporting System. This reporting system captured up to a thousand cases of arrhythmias attributed to hydroxychloroquine use. In fact, the number is likely higher than that, since the reporting system, which requires physicians or patients to initiate contact with the FDA, appreciably undercounts drug side effects.
But what the FDA did not announce is that these adverse events were generated from tens of millions of patient uses of hydroxychloroquine for long periods of time, often for the chronic treatment of lupus or rheumatoid arthritis. Even if the true rates of arrhythmia are ten-fold higher than those reported, the harms would be minuscule compared to the mortality occurring right now in inadequately treated high-risk COVID-19 patients. This fact is proven by an Oxford University study of more than 320,000 older patients taking both hydroxychloroquine and azithromycin, who had arrhythmia excess death rates of less than 9/100,000 users, as I discuss in my May 27 paper cited above. A new paper in the American Journal of Medicine by established cardiologists around the world fully agrees with this.
In the future, I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence. But for now, reality demands a clear, scientific eye on the evidence and where it points. For the sake of high-risk patients, for the sake of our parents and grandparents, for the sake of the unemployed, for our economy and for our polity, especially those disproportionally affected, we must start treating immediately.
Harvey A. Risch, MD, PhD, is professor of epidemiology at Yale School of Public Health.
The views expressd in this article are the writer's own.
<time datetime="2020-07-23T07:00:02-04:00" data-timestamp="1595502002"> On 7/23/20 at 7:00 AM EDT
</time>As professor of epidemiology at Yale School of Public Health, I have authored over 300 peer-reviewed publications and currently hold senior positions on the editorial boards of several leading journals. I am usually accustomed to advocating for positions within the mainstream of medicine, so have been flummoxed to find that, in the midst of a crisis, I am fighting for a treatment that the data fully support but which, for reasons having nothing to do with a correct understanding of the science, has been pushed to the sidelines. As a result, tens of thousands of patients with COVID-19 are dying unnecessarily. Fortunately, the situation can be reversed easily and quickly.
I am referring, of course, to the medication hydroxychloroquine. When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective, especially when given in combination with the antibiotics azithromycin or doxycycline and the nutritional supplement zinc.
On May 27, I published an article in the American Journal of Epidemiology (AJE) entitled, "Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis." That article, published in the world's leading epidemiology journal, analyzed five studies, demonstrating clear-cut and significant benefits to treated patients, plus other very large studies that showed the medication safety.
Physicians who have been using these medications in the face of widespread skepticism have been truly heroic. They have done what the science shows is best for their patients, often at great personal risk. I myself know of two doctors who have saved the lives of hundreds of patients with these medications, but are now fighting state medical boards to save their licenses and reputations. The cases against them are completely without scientific merit.
Since publication of my May 27 article, seven more studies have demonstrated similar benefit. In a lengthy follow-up letter, also published by AJE, I discuss these seven studies and renew my call for the immediate early use of hydroxychloroquine in high-risk patients. These seven studies include: an additional 400 high-risk patients treated by Dr. Vladimir Zelenko, with zero deaths; four studies totaling almost 500 high-risk patients treated in nursing homes and clinics across the U.S., with no deaths; a controlled trial of more than 700 high-risk patients in Brazil, with significantly reduced risk of hospitalization and two deaths among 334 patients treated with hydroxychloroquine; and another study of 398 matched patients in France, also with significantly reduced hospitalization risk. Since my letter was published, even more doctors have reported to me their completely successful use.
My original article in the AJE is available free online, and I encourage readers—especially physicians, nurses, physician assistants and associates, and respiratory therapists—to search the title and read it. My follow-up letter is linked there to the original paper.
Beyond these studies of individual patients, we have seen what happens in large populations when these drugs are used. These have been "natural experiments." In the northern Brazil state of Pará, COVID-19 deaths were increasing exponentially. On April 6, the public hospital network purchased 75,000 doses of azithromycin and 90,000 doses of hydroxychloroquine. Over the next few weeks, authorities began distributing these medications to infected individuals. Even though new cases continued to occur, on May 22 the death rate started to plummet and is now about one-eighth what it was at the peak.
<figure class="imageBox" style=""> <source type="image/webp" media="(min-width: 992px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/jpeg" media="(min-width: 992px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/webp" media="(min-width: 768px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=900&f=7ac996341f797b5565a3461434971a96 1x"><source type="image/jpeg" media="(min-width: 768px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=900&f=7ac996341f797b5565a3461434971a96 1x"><source type="image/webp" media="(min-width: 481px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/jpeg" media="(min-width: 481px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=790&f=609ee90678e61ba1e88036e3539440c1 1x"><source type="image/webp" media="(min-width: 0px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=450&f=b4592c433b66d9a7442394696cfe6def 1x"><source type="image/jpeg" media="(min-width: 0px)" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.jpg?w=450&f=b4592c433b66d9a7442394696cfe6def 1x"><source type="image/webp" data-srcset="https://d.newsweek.com/en/full/1612004/hydroxychloroquine-tablets.webp?w=790&f=609ee90678e61ba1e88036e3539440c1"> <figcaption class="caption"> </figcaption>
</figure>A reverse natural experiment happened in Switzerland. On May 27, the Swiss national government banned outpatient use of hydroxychloroquine for COVID-19. Around June 10, COVID-19 deaths increased four-fold and remained elevated. On June 11, the Swiss government revoked the ban, and on June 23 the death rate reverted to what it had been beforehand. People who die from COVID-19 live about three to five weeks from the start of symptoms, which makes the evidence of a causal relation in these experiments strong. Both episodes suggest that a combination of hydroxychloroquine and its companion medications reduces mortality and should be immediately adopted as the new standard of care in high-risk patients.
Why has hydroxychloroquine been disregarded?
First, as all know, the medication has become highly politicized. For many, it is viewed as a marker of political identity, on both sides of the political spectrum. Nobody needs me to remind them that this is not how medicine should proceed. We must judge this medication strictly on the science. When doctors graduate from medical school, they formally promise to make the health and life of the patient their first consideration, without biases of race, religion, nationality, social standing—or political affiliation. Lives must come first.
Second, the drug has not been used properly in many studies. Hydroxychloroquine has shown major success when used early in high-risk people but, as one would expect for an antiviral, much less success when used late in the disease course. Even so, it has demonstrated significant benefit in large hospital studies in Michigan and New York City when started within the first 24 to 48 hours after admission.
In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.
In fact, as inexpensive, oral and widely available medications, and a nutritional supplement, the combination of hydroxychloroquine, azithromycin or doxycycline, and zinc are well-suited for early treatment in the outpatient setting. The combination should be prescribed in high-risk patients immediately upon clinical suspicion of COVID-19 disease, without waiting for results of testing. Delays in waiting before starting the medications can reduce their efficacy.
Third, concerns have been raised by the FDA and others about risks of cardiac arrhythmia, especially when hydroxychloroquine is given in combination with azithromycin. The FDA based its comments on data in its FDA Adverse Event Reporting System. This reporting system captured up to a thousand cases of arrhythmias attributed to hydroxychloroquine use. In fact, the number is likely higher than that, since the reporting system, which requires physicians or patients to initiate contact with the FDA, appreciably undercounts drug side effects.
But what the FDA did not announce is that these adverse events were generated from tens of millions of patient uses of hydroxychloroquine for long periods of time, often for the chronic treatment of lupus or rheumatoid arthritis. Even if the true rates of arrhythmia are ten-fold higher than those reported, the harms would be minuscule compared to the mortality occurring right now in inadequately treated high-risk COVID-19 patients. This fact is proven by an Oxford University study of more than 320,000 older patients taking both hydroxychloroquine and azithromycin, who had arrhythmia excess death rates of less than 9/100,000 users, as I discuss in my May 27 paper cited above. A new paper in the American Journal of Medicine by established cardiologists around the world fully agrees with this.
In the future, I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence. But for now, reality demands a clear, scientific eye on the evidence and where it points. For the sake of high-risk patients, for the sake of our parents and grandparents, for the sake of the unemployed, for our economy and for our polity, especially those disproportionally affected, we must start treating immediately.
Harvey A. Risch, MD, PhD, is professor of epidemiology at Yale School of Public Health.
The views expressd in this article are the writer's own.
So a positive HCQ azithro study comes out, pretty much crickets. A negative HCQ study comes, gets published immediately by the usual suspects.
https://www.google.com/amp/s/amp.cn...roxychloroquine-covid-brazil-study/index.html
Once again a very flawed study and backed by their equivalent of our gilead. HCQ and Azithro (no zinc) given after 7 or 8 days of first symptom. Too late. There were other flaws but it's late and this is bullshit. It really is criminal.
https://www.google.com/amp/s/amp.cn...roxychloroquine-covid-brazil-study/index.html
Once again a very flawed study and backed by their equivalent of our gilead. HCQ and Azithro (no zinc) given after 7 or 8 days of first symptom. Too late. There were other flaws but it's late and this is bullshit. It really is criminal.
