People put too much stock into the back to back/4 games in 6 days stuff. We're talking about players in great physical condition in their early 20's, for the most part.
It depends on the situation.
There are times where scheduling situations like this absolutely have an effect. Most of my profitable angles have to do with Home Dogs, which obviously tonight isn't. With a road dog ion this range, its a negligible effect. Around a 50-50 proposition. So while it may not matter tonight, it absolutely matters in some situations.
Cavaliers have been terrible this season against the spread when they are double-digit dogs. When the Cavs are spotted 10 or more points this season they are 1-4 ATS.
That is certainly true.
Consider that unrested road dogs playing 4 in 6 days coming off a home game are just 41-81 ATS (33.6%) over the last ten seasons, when facing an opponent coming off a home loss. Teams this year are 1-7 ATS in this situation. Facing a mad opponent like the Thunder who are coming off two home losses, doesn't look like the sweetest spot. The Thunder are 17-1 with an average winning margin of 16.78 when playing as a double digit favorite at home off a loss, and they are 15-3 ATS. Kyrie isn't happy and that doesn't bode well for team chemistry.
Seems like a fair line.
Good luck