Lions shouldn't be a TD favorite to anyone, but I agree this will be a tough game for a rookie QB making his first start on the road. ESPN states Darnold is the youngest QB to start week 1, the first rookie QB to start on MNF week1, and here's what happened to all the other youngsters who made their first start during week1.
From ESPN:
2018 Sam Darnold 21 years, 97 days ?
1993 Drew Bledsoe 21 years, 203 days Lost
2009 Matthew Stafford21 years, 218 days Lost
2017 DeShone Kizer 21 years, 250 days Lost
2015 Jameis Winston 21 years, 250 days Lost
Looks like the Jets are going to lose tonight, but by how many points?