NCAAF Week 4 Picks for Three Top-Ranking Teams’ Matchups

Bryce Young Alabama Crimson Tide Louisiana Monroe Warhawks
Bryce Young #9 of the Alabama Crimson Tide reacts after passing for a touchdown against the Louisiana Monroe Warhawks. Kevin C. Cox/Getty Images/AFP.

This week, many college football teams play conference openers. Even teams who had upset losses can still run the table and win conference championships, and that will put them in contention to play in major bowl games.

Alabama hosts the Vanderbilt Commodores, one of the biggest surprises in the SEC. Ohio State will be tested by a gritty Wisconsin team, and Oklahoma will face off against Kansas State.

In these three games, we have three heavy favorites. However, plenty of conference opponents keep games close. Can we expect an upset with these three big games? Let’s break down the details for each game and their respective NFL picks.

Vanderbilt Commodores vs. Alabama Crimson Tide

Saturday, September 24. 2022 – 07:30 PM EDT at Bryant-Denny Stadium

Teams Analysis

Alabama looked dominant against the Warhawks last week, but this is the Tide’s first SEC game of the year.

Alabama will be looking to send a statement to SEC contenders by beating up on one of the worst teams in the conference.

However, Vanderbilt has looked significantly better this year. They traveled to Hawaii in their season opener and came out with a strong victory.

They have three wins in the first four games, and they’ll be looking to keep this one competitive for as long as possible.

Vanderbilt vs. Alabama: Pick and Prediction

Expecting Vanderbilt to upset the Tide is ludicrous, but can Vandy at least keep things competitive? With all due respect, I doubt it. Alabama will not let off on the gas against an SEC opponent. The offense is healthier now than they were to start the season, and Jahmyr Gibbs looks unstoppable.

Will Anderson and the Tide defense look to prove a point in this game. The secondary has question marks, but Terrion Arnold proved to be a valuable asset as a starter last year. With so many potential contributors, the Tide should be able to find five defensive backs for nickel coverage.

I like Alabama to cover this spread because of the simple gap in talent between the two rosters.

NCAAF Pick: Alabama -39 (-115) at DraftKings


Wisconsin Badgers vs. Ohio State Buckeyes

Saturday, September 24, 2022 – 07:30 PM EDT at Ohio Stadium

Teams Analysis

Ohio State has been playing well this year, but it has not translated to covering the spread. The Buckeyes are 1-2 ATS this season despite three strong wins.

However, this spread is smaller than they have seen in a bit. Many are expecting Wisconsin to slowly churn out the clock while running the ball and limiting the total number of drives.

Wisconsin vs. Ohio State: Pick and Prediction

Ohio State can play at any pace with CJ Stroud under center. But I don’t like the spread in this game. Wisconsin will be looking to play slowly, and this will make it hard for Ohio State to cover.

Still, the Buckeyes are significantly better. I don’t like battling wills like this when looking for value on a point spread.

Instead, I like for the Under to hit. There is a high chance of the Badgers struggling offensively, and this points total is high enough that both teams will need to score consistently to hit.

NCAAF Pick: Under 57.5 (-110) at BetMGM


Kansas State Wildcats vs. Oklahoma Sooners

Saturday, September 24, 2022 – 08:00 PM EDT at Oklahoma Memorial Stadium

Teams Analysis

Neither team has hit the Over yet this season, but the totals line is not ideal to bet in this game. Instead, I like the Sooners to cover the spread. This is a small spread for a team coming off of a dominant win and playing at home.

The Wildcats are coming off of an embarrassing performance last week, and I don’t see them bouncing back against the Sooners’ defense. Venables has revamped this squad quickly, and Dillon Gabriel is leading the offense every Saturday.

Kansas State vs. Oklahoma: Picks and Prediction

Oklahoma deserves more credit for such a strong start to the season. They could easily be the Big 12 champs this season. They’ll start with a large win against Kansas State.

NCAAF Pick: Oklahoma -10.5 (-169) at SBK